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KMID : 1059519930370090837
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Journal of the Korean Chemical Society
1993 Volume.37 No. 9 p.837 ~ p.844
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Synthesis of N-Hydroxy-α-Amino Acid Esters
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Seo Min-Hyo
Wang Han-Cheol
Lee Yun-Yeong
Goo Yang-Mo
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Abstract
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N-Arylmethylideneglycine N-oxide alkyl esters(1) were alkylated with alkyl halides in THF using lithium hexamethyldisilazide as a base, followed by hydroxylaminolysis to give N-hydroxy-α-amino acid esters(7).
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